This qualitative research study builds on JCOIN026 (Brief Stigma Surveys) by conducting interviews with AmeriSpeak participants based on their OUD stigma scores to learn more about why they hold their respective levels of stigma towards people with OUD. Interviews will be conducted with participants who report strongly endorsing stigmatizing attitudes toward individuals with OUD and those who do not endorse stigmatizing attitudes toward individuals with OUD. The goal of this study is to try to get to the root causes of these stigmatizing attitudes and to ascertain protective factors among those without stigma or factors that resulted in reduced stigma. Findings from this study will be used to further explain results of the AmeriSpeak survey in a multi-methods manuscript that includes recommendations for messaging.